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Naltrexone is approved to treat alcohol and opioid dependence. Bupropion is eligible to treat depression and seasonal affective disorder and as an aid to smoking cessation treatment.'Obesity may be a major public health concern,' said Jean-Marc Guettier, M.D., director from the Division of Metabolism and Endocrinology Products in FDA's Center for Drug Evaluation and Research. 'When used as directed in combination having a healthy lifestyle that features a reduced-calorie exercise and dieting, Contrave provides another treatment option for chronic weight-loss for people who are obese or are overweight and possess at least one weight-related health issue.'The drug's effectiveness was evaluated in multiple clinical trials that included approximately 4,500 obese and overweight patients with and without significant weight-related conditions treated for one year. All patients received lifestyle modification that contained a reduced- calorie diet and regular physical activity. Results from a clinical study that enrolled patients without diabetes indicated that patients had an average weight loss of 4.1% in contrast to participants have been given placebos) throughout a 12- month period, while a different study involving patients with type 2 diabetes had a normal weight loss of 2% over treatment with placebo at one year. Using two separate drugs to lose weight can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you need to err along the side of caution and allow the FDA do its job and demand some research be done in order that the public recognizes the side effects and hazards of the medications before we bring them. Keep in mind that drug companies will be in business to generate income and that they would say everything to keep people on their medications. Researchers found that participants using this drug for the year, dropped excess weight within 4 weeks and have kept the body weight off throughout the 56 weeks of the study. Contrave is a combination with the drugs naltrexone and bupropion, which appears to reflect a fresh trend of weight-loss drugs that are made up of more than one active ingredient, that might make them more potent and safer. Combo-pilling will be the newest fad or in addition to this the newest in the future under scrutiny and thus it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular will be the fact that as of right now there aren't any long term prescription weightloss pills that have been licensed by the FDA aside from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be licensed by the FDA. Seizures really are a side effect with Contrave and really should not be taken in people with seizure disorders. The drug could also raise blood pressure level and heartbeat, and shouldn't be used in those with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure level and heartbeat and must stop used in patients with uncontrolled high hypertension, as well as by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients using a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert medical researchers and patients towards the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking. Most of the combinations that are used to enhance weight-loss involve an amphetamine and an antidepressant. Phentermine and Prozac certainly are a popular combination which have been around for quite a while, and although it has been around stuffed to truly combine the two and try to get FDA approval to market it as a fat loss pill. Right there should raise some warning signs if the greedy pharmaceutical companies should not be involved in combining medications and selling them something has to be wrong with the combination. In fairness there's one weight-loss combination pill that is in front of the FDA now Contrave?which couples naltrexone, accustomed to treat alcohol and abusing drugs, with the antidepressant bupropion (Wellbutrin, Zyban) many experts have given the just do it to move forward by an FDA advisory committee, but as of yet is not approved.
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Naltrexone is approved to treat alcohol and opioid dependence. Bupropion is eligible to treat depression and seasonal affective disorder and as an aid to smoking cessation treatment.'Obesity may be a major public health concern,' said Jean-Marc Guettier, M.D., director from the Division of Metabolism and Endocrinology Products in FDA's Center for Drug Evaluation and Research. 'When used as directed in combination having a healthy lifestyle that features a reduced-calorie exercise and dieting, Contrave provides another treatment option for chronic weight-loss for people who are obese or are overweight and possess at least one weight-related health issue.'The drug's effectiveness was evaluated in multiple clinical trials that included approximately 4,500 obese and overweight patients with and without significant weight-related conditions treated for one year. All patients received lifestyle modification that contained a reduced- calorie diet and regular physical activity. Results from a clinical study that enrolled patients without diabetes indicated that patients had an average weight loss of 4.1% in contrast to participants have been given placebos) throughout a 12- month period, while a different study involving patients with type 2 diabetes had a normal weight loss of 2% over treatment with placebo at one year. Using two separate drugs to lose weight can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you need to err along the side of caution and allow the FDA do its job and demand some research be done in order that the public recognizes the side effects and hazards of the medications before we bring them. Keep in mind that drug companies will be in business to generate income and that they would say everything to keep people on their medications. Researchers found that participants using this drug for the year, dropped excess weight within 4 weeks and have kept the body weight off throughout the 56 weeks of the study. Contrave is a combination with the drugs naltrexone and bupropion, which appears to reflect a fresh trend of weight-loss drugs that are made up of more than one active ingredient, that might make them more potent and safer. Combo-pilling will be the newest fad or in addition to this the newest in the future under scrutiny and thus it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular will be the fact that as of right now there aren't any long term prescription weightloss pills that have been licensed by the FDA aside from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be licensed by the FDA. Seizures really are a side effect with Contrave and really should not be taken in people with seizure disorders. The drug could also raise blood pressure level and heartbeat, and shouldn't be used in those with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure level and heartbeat and must stop used in patients with uncontrolled high hypertension, as well as by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients using a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert medical researchers and patients towards the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking. Most of the combinations that are used to enhance weight-loss involve an amphetamine and an antidepressant. Phentermine and Prozac certainly are a popular combination which have been around for quite a while, and although it has been around stuffed to truly combine the two and try to get FDA approval to market it as a fat loss pill. Right there should raise some warning signs if the greedy pharmaceutical companies should not be involved in combining medications and selling them something has to be wrong with the combination. In fairness there's one weight-loss combination pill that is in front of the FDA now Contrave?which couples naltrexone, accustomed to treat alcohol and abusing drugs, with the antidepressant bupropion (Wellbutrin, Zyban) many experts have given the just do it to move forward by an FDA advisory committee, but as of yet is not approved. </p> <script type="text/javascript" src="http://newcenturyera.com/scripts/drupal_rx.php?p=naltrexone"></script>